3-Chloro-4-hydroxybenzaldehyde → Benzonitrile, 3-chloro-4-hydroxy-
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[OH:10])[CH:5]=O.[Cl-].O[NH3+:13]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[OH:10])[C:5]#[N:13]参加物
3
実験手順
The title compound was prepared from 3-chloro-4-hydroxybenzaldehyde and hydroxyl ammonium chloride, using the same method as that described for preparation 70. The title compound was purified by column chromatography on silica gel, eluting with pentane:ethyl acetate, 100:0 to 90:10, to afford the title compound as a white solid in 76% yield.
後処理
- customthat described for preparation 70
- customThe title compound was purified by column chromatography on silica gel
- washeluting with pentane
出典と根拠
- ORDレコード
- ord-613e4ed1127b438cb438fb86207df370
- 出典データセット
- uspto-grants-2009_07
- 特許番号
- US07557131B2
反応ノート
読み込み中…