塩酸ヒドロキシルアミン

解説塩酸ヒドロキシルアミン，無色の単斜晶系結晶．[NH3OH]＋ を含むイオン結晶．密度約1.68 g cm－3．N-O約1.45 Å，N…Cl約3.16，3.21，3.23 Å．融点152 ℃(分解)．湿気のある空中では徐々に分解する．水，液体アンモニアに易溶，メタノール，エタノールに可溶，エーテルに不溶．水溶液中でしだいに分解していく．還元性がある．ケトン，アルデヒドとオキシムをつくる．ヒドロキシルアミンの原料，合成，分析用試薬に用いられる．そのほか，写真用還元剤，せっけん，脂肪酸の酸化防止剤，酵素の再活性化剤などにも用いられる．

用途半導体の剥離剤，医薬?カプロラクタム原料

用途還元剤、医薬品原料

用途比色分析のための鉄及び銅の還元剤。

用途有害金属の原子吸光分析における還元剤。

用途還元剤、酸化防止剤、調製液添加剤、有機合成原料。

説明Hydroxylamine hydrochloride is a reducing agent that is routinely used for the deacetylation of SATA to form free sulfhydryls (Figure 1), for cleavage of protein cross‐linkers that contain carbonyl groups (i.e. EGS) and for mutagenesis of plasmid DNA.Hydroxylamine converts aldehydes and ketones (carbonyls) to their oxime derivative in weak bases, therefore cross‐linkers and other compounds with carbonyl groups are cleavable with Hydroxylamine hydrochloride.SATA and SATP are modification reagents that add a sulfhydryl group to primary amines on biomolecules. The initial modification results in the addition of an acetyl‐protected sulfur enabling storage of the biomolecule. To generate a free sulfhydryl the biomolecule is treated with hydroxylamine to remove the protecting acetyl group (see figure).EGS and sulfo‐EGS are homobifunctional, succinimidyl ester, amine reactive crosslinkers that are resistant to cleavage by denaturants used in SDS‐PAGE conditions, but may be cleaved with hydroxylamine.

使用Hydroxylamine hydrochloride is a monomoamine oxidase inhibitor. It is used to prepare oximes and hydroxmic acids in organic synthesis. It acts as a copolymerization inhibitor. It can be used to remove bromine and polybromide from a solution during extraction of lignin from lignocellulosic biomass. It is key starting material for the preparation of pharmaceuticals and agrochemicals. It plays a vital role in rubber and plastic industries as an antioxidant, a vulcanization accelerator and a radical scavenger. It is also used as a color stabilizer and emulsion additive in color films.