Methyl iodide → 3-Bromothioanisole
反応式
[Br:1][C:2]1[CH:3]=[C:4]([SH:8])[CH:5]=[CH:6][CH:7]=1.[C:9](=O)([O-])[O-].[K+].[K+].IC>CC(C)=O>[CH3:9][S:8][C:4]1[CH:3]=[C:2]([Br:1])[CH:7]=[CH:6][CH:5]=1参加物
5
実験手順
To a solution of 3-bromothiophenol (10 g) in acetone (250 mL) was added potassium carbonate (14.6 g) and iodomethane (4.28 mL). The heterogenous mixture was refluxed for 4 hrs., cooled to room temperature, filtered, and concentrated under reduced pressure. Ether (200 mL) was added, and the mixture was filtered again and finally evaporated to dryness to yield the title compound.
後処理
- temperatureThe heterogenous mixture was refluxed for 4 hrs
- filtrationfiltered
- concentrationconcentrated under reduced pressure
- additionEther (200 mL) was added
- filtrationthe mixture was filtered again
- customfinally evaporated to dryness
出典と根拠
- ORDレコード
- ord-581984c1318441db9e89fd4f881319b7
- 出典データセット
- uspto-grants-1995_06
- 特許番号
- US05428171
反応ノート
読み込み中…