Dichloromethane → HCID 19002930、化合物
反応式
C[Si](C)(C)[C:3]1[O:11][C:10]2[C:5](=[N:6][C:7]([CH3:12])=[CH:8][CH:9]=2)C=1.[Cl:15]N1C(=O)N(Cl)C(=O)N(Cl)C1=O.CCOC(C)=O.[CH2:33]([Cl:35])Cl>CCCCCC>[Cl:15][C:3]1[O:11][C:10]2[C:5](=[N:6][C:7]([CH3:12])=[CH:8][CH:9]=2)[C:33]=1[Cl:35]参加物
6
反応条件
- 温度
- 0 °C
実験手順
To a solution of 2-trimethylsilyl-5-methylfurano[3,2-b]pyridine (1.05 g, 5.15 mmol) in CH2Cl2 (16 mL) at 0° C. was added trichloroisocyanuric acid (1.2 g, 5.15 mmol). The mixture was stirred at 0° C. for 30 rain and then at r.t. for 20 hr. A solution of 30% EtOAc in hexane was added. The resulting mixture was filtered through a short bed of silica gel and eluted with more 30% EtOAc in hexane. Evaporation of the filtrate gave 1.0 g (96%) of the title compound.
後処理
- filtrationThe resulting mixture was filtered through a short bed of silica gel
- washeluted with more 30% EtOAc in hexane
- customEvaporation of the filtrate
出典と根拠
- ORDレコード
- ord-0b2b9cb5b35d403da2a02636feebfe8b
- 出典データセット
- uspto-grants-1995_12
- 特許番号
- US05472964
反応ノート
読み込み中…