化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Hydroxide → N-(2,3-dihydroxypropyl)-N-hexadecyl-2-hydroxyoctanamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | 3-(Hexadecylamino)propane-1,2-diol | HCID 111007 | — |
| 反応物 | Methyl 2-hydroxyoctanoate | HCID 10487462 | — |
| 生成物 | N-(2,3-dihydroxypropyl)-N-hexadecyl-2-hydroxyoctanamide | HCID 10217103 | — |
反応手順
N-(2,3-dihydroxypropyl)-hexadecylamine (1.0 g, 3.2 mmoles) and potassium hydroxide (0.01 g, 0.18 mmoles) were heated to 85° C. under vacuum and methyl-2-hydroxyoctanoate (0.55 g, 3.2 mmoles) was added dropwise to the reaction. The reaction was heated under vacuum for 6 hours. A waxy off white solid was obtained (crude yield=1,39 g), and the waxy solid further purified by recrystallization in hot hexane. (Yield=0.88g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05476661 |
| 出典データセット | uspto-grants-1995_12 |
| ORD ID | ord-a7d2978f0e4e4f0da0d2ac2365b13e60 |
| 出典メモ | uspto-grants-1995_12 |