Glycidol → 3-(Octadecylamino)propane-1,2-diol

HRID 2260084

反応式

HRID 2260084 の反応式
[CH2:1]([NH2:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH2:20]1[O:22][CH:21]1[CH2:23][OH:24]>C(O)C>[OH:22][CH:21]([CH2:23][OH:24])[CH2:20][NH:19][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

参加物

4

反応物 2

HCID 11164GlycidolHCID 15793Octadecylamine

生成物 1

HCID 1200883-(Octadecylamino)propane-1,2-diol

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Octadecylamine (9.09 g, 0.034 mole) was dissolved in absolute ethanol. Glycidol (5.00 g, 0.068 mole) was added to the amine dropwise. The reaction solution was refluxed under nitrogen for 4 hours and then was stirred overnight at room temperature. A white solid was obtained (crude yield=10.8 g). The solid was recrystalized from hot hexane. (Yield=6.9 g).

後処理

  1. temperatureThe reaction solution was refluxed under nitrogen for 4 hours
  2. customA white solid was obtained (crude yield=10.8 g)
  3. customThe solid was recrystalized from hot hexane

出典と根拠

ORDレコード
ord-2093b14d28454a6cadc580b9c2ddb3ce
出典データセット
uspto-grants-1995_12
特許番号
US05476671

関連ノート

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