Diisopropylaniline → Dibenz(b,e)oxepin-11-carboxamide, 6,11-dihydro-N-(2,6-bis(1-methylethyl)phenyl)-2-methyl-

HRID 2260576

反応式

HRID 2260576 の反応式
[CH3:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][CH2:7][C:8]3[CH:17]=[CH:16][CH:15]=[CH:14][C:9]=3[CH:10]([C:11](O)=[O:12])[C:4]=2[CH:3]=1.[CH:20]([C:23]1[CH:29]=[CH:28][CH:27]=[C:26]([CH:30]([CH3:32])[CH3:31])[C:24]=1[NH2:25])([CH3:22])[CH3:21]>>[CH:30]([C:26]1[CH:27]=[CH:28][CH:29]=[C:23]([CH:20]([CH3:22])[CH3:21])[C:24]=1[NH:25][C:11]([CH:10]1[C:9]2[CH:14]=[CH:15][CH:16]=[CH:17][C:8]=2[CH2:7][O:6][C:5]2[CH:18]=[CH:19][C:2]([CH3:1])=[CH:3][C:4]1=2)=[O:12])([CH3:32])[CH3:31]

参加物

3

反応物 2

HCID 32484DiisopropylanilineHCID 101063426,11-Dihydro-2-methyldibenz[b,e]-oxepin-11-carboxylic acid

生成物 1

HCID 3072807Dibenz(b,e)oxepin-11-carboxamide, 6,11-dihydro-N-(2,6-bis(1-methylethyl)phenyl)-2-methyl-収率 94.8%

実験手順

The similar procedures as in Example 1 were repeated except using 1.20 g of Compound A and 1.00 g of 2,6-diisopropylaniline in place of aniline to obtain 1.85 g of Compound 4.

出典と根拠

ORDレコード
ord-331cf4583d0546198a0894dcfb6724b2
出典データセット
uspto-grants-1995_12
特許番号
US05478835

関連ノート

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