Thionyl Chloride → HCID 57736386、化合物
反応式
[CH3:1][C:2]([C:8]1[O:12][N:11]=[C:10]([CH2:13]O)[CH:9]=1)([O:4][CH2:5][C:6]#[CH:7])[CH3:3].S(Cl)([Cl:17])=O>ClCCl>[Cl:17][CH2:13][C:10]1[CH:9]=[C:8]([C:2]([CH3:3])([O:4][CH2:5][C:6]#[CH:7])[CH3:1])[O:12][N:11]=1参加物
4
実験手順
0.20 g of {5-[1-methyl-1-(2-propynyloxy)ethyl]isoxazol-3-yl}methanol was dissolved in 5 ml of dichloromethane, and 0.5 ml of thionyl chloride was then added. The mixture was stirred at room temperature for 3 hours. The reaction mixture was concentrated under reduced pressure to obtain 0.21 g of 3-(chloromethyl)-5-[1-methyl-1-(2-propynyloxy)ethyl]isoxazole.
後処理
- concentrationThe reaction mixture was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-620532568c8f44e28062fb5ab23dc71d
- 出典データセット
- uspto-grants-2010_12
- 特許番号
- US07846956B2
反応ノート
読み込み中…