Selenium → 7-Methoxy-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one
反応式
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH2:16][CH2:15][C:10]3=[N:11][CH:12]=[CH:13][CH:14]=[C:9]3[C:8](=[O:17])[C:7]=2[CH:18]=1.[Se]>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH:16]=[CH:15][C:10]3=[N:11][CH:12]=[CH:13][CH:14]=[C:9]3[C:8](=[O:17])[C:7]=2[CH:18]=1参加物
4
反応条件
- 温度
- 120 °C
実験手順
A mixture of 2.3 g (9.6 mmol) of the product from Example 23 step 4, 1.85 g (16.6 mmol) of selenium dioxyde and 5 ml of pyridine is stirred at 120° C. for 6 hr. The whole is poured into excess petroleum ether and the solution is evaporated giving 0.55 g (24%) of enough pure title product as to prosecute with the synthesis.
後処理
- customthe solution is evaporated
出典と根拠
- ORDレコード
- ord-927970835fe54928acc167750afbfec8
- 出典データセット
- uspto-grants-2009_07
- 特許番号
- US07557212B2
反応ノート
読み込み中…