Water → 2-(2-Chlorophenyl)-2-oxoethyl thiocyanate

HRID 2263313ノート

反応式

HRID 2263313 の反応式
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11])=[O:4].[S-:12][C:13]#[N:14].[K+].O>C(O)C>[Cl:11][C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=1[C:3](=[O:4])[CH2:2][S:12][C:13]#[N:14]

参加物

5

反応物 3

HCID 962WaterHCID 516872Potassium thiocyanateHCID 27357852-Bromo-2'-chloroacetophenone

生成物 1

HCID 242137572-(2-Chlorophenyl)-2-oxoethyl thiocyanate収率 75.3%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 2-bromo-1-(2-chlorophenyl)ethanone (7.55 g, 32.3 mmol) and potassium thiocyanate (3.14 g, 32.3 mmol) in ethanol (70 ml) was stirred at 80° C. for 2 hours. After cooling to room temperature, water (70 ml) was poured to the reaction mixture, and crystals were collected by filtration and washed with water to give 5.15 g (75.3%) of the desired product as a solid.

後処理

  1. filtrationwere collected by filtration
  2. washwashed with water

出典と根拠

ORDレコード
ord-bf9526e7ef8447539045f76933e9ab5f
出典データセット
uspto-grants-2010_12
特許番号
US07851473B2

反応ノート

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