HCID 59596015、化合物 → HCID 59595986、化合物

HRID 2264191ノート

反応式

HRID 2264191 の反応式
[N+:1]([C:4]1[CH:5]=[C:6]([C:16]2[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=2)[C:7]([C:11]2[O:12][CH:13]=[CH:14][N:15]=2)=[N:8][C:9]=1[NH2:10])([O-])=O>[Pd].C(O)C>[O:12]1[CH:13]=[CH:14][N:15]=[C:11]1[C:7]1[C:6]([C:16]2[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=2)=[CH:5][C:4]([NH2:1])=[C:9]([NH2:10])[N:8]=1

参加物

4

反応物 1

HCID 59596015HCID 59596015、化合物

生成物 1

HCID 59595986HCID 59595986、化合物収率 98.1%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A suspension of 5-nitro-2-(1,3-oxazol-2-yl)-3,4′-bipyridin-6-amine (0.089 g, 0.31 mmol) and palladium on carbon (10%, 20 mg) in ethanol (15 mL) was placed under a hydrogen atmosphere (balloon) and stirred at room temperature. After 3 hours, the mixture was filtered through Celite® and the filtrate was evaporated. Trituration with diethyl ether gave the title compound (0.077 g, 97%) as a pale orange solid.

後処理

  1. filtrationthe mixture was filtered through Celite®
  2. customthe filtrate was evaporated

出典と根拠

ORDレコード
ord-e57fe1f34ca0402585c6297631c2564a
出典データセット
uspto-grants-2010_12
特許番号
US07855202B2

反応ノート

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