1-(Bromomethyl)-4-chlorobenzene → 2-(4-chlorobenzyl)-3-oxothiobutyric Acid S-tert-butyl Ester

反応式

Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([Cl:9])=[CH:5][CH:4]=1.[C:10]([S:14][C:15](=[O:20])[CH2:16][C:17](=[O:19])[CH3:18])([CH3:13])([CH3:12])[CH3:11]>>[C:10]([S:14][C:15](=[O:20])[CH:16]([CH2:2][C:3]1[CH:8]=[CH:7][C:6]([Cl:9])=[CH:5][CH:4]=1)[C:17](=[O:19])[CH3:18])([CH3:13])([CH3:11])[CH3:12]

参加物

反応物 2

HCID 693291-(Bromomethyl)-4-chlorobenzene

HCID 140007Butanethioic acid, 3-oxo-, S-(1,1-dimethylethyl) ester

生成物 1

HCID 866314362-(4-chlorobenzyl)-3-oxothiobutyric Acid S-tert-butyl Ester

実験手順

The title compound was prepared by the method of Preparation 34a using 1-bromomethyl-4-chlorobenzene and 3-oxothiobutyric acid S-tert-butyl ester.

出典と根拠

ORDレコード: ord-3501a3257c5b44e6a5c0765fa00db8d6
出典データセット: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07858640B2

反応ノート

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