Oxalyl chloride → 5-Bromo-3-chloro-2,4-difluorobenzoyl chloride
反応式
[Br:1][C:2]1[C:3]([F:13])=[C:4]([Cl:12])[C:5]([F:11])=[C:6]([CH:10]=1)[C:7](O)=[O:8].C(Cl)(=O)C([Cl:17])=O>ClCCl.CN(C=O)C>[Br:1][C:2]1[C:3]([F:13])=[C:4]([Cl:12])[C:5]([F:11])=[C:6]([CH:10]=1)[C:7]([Cl:17])=[O:8]参加物
5
実験手順
A quantity of 5.2 g of 5-bromo-3-chloro-2,4-difluorobenzoic acid is suspended in 30 ml of dichloromethane; then 2.92 g of oxalyl chloride is added, and 3 drops of dry DMF are added. The mixture is stirred at room temperature for 3 hours and the desired compound is isolated after evaporation of the solvent.
出典と根拠
- ORDレコード
- ord-52210b12637c47c18436beba4d1639fe
- 出典データセット
- uspto-grants-2001_12
- 特許番号
- US06329391B1
反応ノート
読み込み中…