(3-Nitrophenyl)-thiophen-2-ylmethanone → N-[1-(3,4-Difluorophenyl)ethyl]-N-[(3-nitrophenyl)-(thiophen-2-yl)methyl}amine

HRID 2269485

反応式

HRID 2269485 の反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([N+:14]([O-:16])=[O:15])[CH:9]=1)=O.[F:17][C:18]1[CH:19]=[C:20]([CH:25]([NH2:27])[CH3:26])[CH:21]=[CH:22][C:23]=1[F:24]>>[F:17][C:18]1[CH:19]=[C:20]([CH:25]([NH:27][CH:6]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([N+:14]([O-:16])=[O:15])[CH:9]=2)[C:2]2[S:1][CH:5]=[CH:4][CH:3]=2)[CH3:26])[CH:21]=[CH:22][C:23]=1[F:24]

参加物

3

反応物 2

HCID 348407(3-Nitrophenyl)-thiophen-2-ylmethanoneHCID 38159741-(3,4-Difluorophenyl)ethanamine

生成物 1

HCID 18347069N-[1-(3,4-Difluorophenyl)ethyl]-N-[(3-nitrophenyl)-(thiophen-2-yl)methyl}amine収率 95%

実験手順

Following a similar procedure to that described in Example (1a), 3.03 g of 3-nitrophenyl thiophen-2-yl ketone and 2.52 g of 1-(3,4-difluorophenyl)ethylamine were reacted, to obtain 4.62 g of the title compound as a reddish orange oil.

後処理

  1. customwere reacted

出典と根拠

ORDレコード
ord-7247e6c2e9d94f76889dc03f811c4f4f
出典データセット
uspto-grants-2001_12
特許番号
US06329405B1

関連ノート

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