Phenol, 4-methoxy-2-nitro- → 2-Amino-4-methoxyphenol
反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[C:5]([N+:10]([O-])=O)[CH:4]=1>CO.[Pd]>[NH2:10][C:5]1[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[CH:7][C:6]=1[OH:9]参加物
4
実験手順
A solution of 4-methoxy-2-nitrophenol 11 (10 g, 59.1 mmol) and Pd/C (1.0 g) in methanol (100 ml) was placed on a Parr shaker under H2 (50 psi) for 60 minutes. The reaction mixture was filtered through Celite 521 and the filter cake washed with MeOH. The filtrate was evaporated (in vacuo), to yield compound 12 as a tan solid.
後処理
- filtrationThe reaction mixture was filtered through Celite 521
- washthe filter cake washed with MeOH
- customThe filtrate was evaporated (in vacuo)
出典と根拠
- ORDレコード
- ord-4d5d8283e50c4141aca07510c1511933
- 出典データセット
- uspto-grants-2005_02
- 特許番号
- US06849632B2
反応ノート
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