Phenol, 4-methoxy-2-nitro- → 2-Amino-4-methoxyphenol

HRID 22698

反応式

HRID 22698 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[C:5]([N+:10]([O-])=O)[CH:4]=1>CO.[Pd]>[NH2:10][C:5]1[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[CH:7][C:6]=1[OH:9]

参加物

4

反応物 1

HCID 15285Phenol, 4-methoxy-2-nitro-

生成物 1

HCID 14191082-Amino-4-methoxyphenol

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

A solution of 4-methoxy-2-nitrophenol 11 (10 g, 59.1 mmol) and Pd/C (1.0 g) in methanol (100 ml) was placed on a Parr shaker under H2 (50 psi) for 60 minutes. The reaction mixture was filtered through Celite 521 and the filter cake washed with MeOH. The filtrate was evaporated (in vacuo), to yield compound 12 as a tan solid.

後処理

  1. filtrationThe reaction mixture was filtered through Celite 521
  2. washthe filter cake washed with MeOH
  3. customThe filtrate was evaporated (in vacuo)

出典と根拠

ORDレコード
ord-4d5d8283e50c4141aca07510c1511933
出典データセット
uspto-grants-2005_02
特許番号
US06849632B2

関連ノート

読み込み中…