Sodium Hydroxide → Sodium 6,8-dihydroxyoctanoate

HRID 2270143ノート

反応式

HRID 2270143 の反応式
[OH:1][CH:2]([CH2:11][CH2:12][OH:13])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9]C)=[O:8].[OH-].[Na+:15]>CO>[OH:1][CH:2]([CH2:11][CH2:12][OH:13])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O-:9])=[O:8].[Na+:15]

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 113559606,8-Dihydroxyoctanoic acid methyl ester

生成物 1

HCID 23714776Sodium 6,8-dihydroxyoctanoate

試薬・触媒・溶媒 1

HCID 887Methanol溶媒2 回

実験手順

Methyl 6,8-dihydroxyoctanoate (0.15 g, 0.80 mmol; containing about 10% of the 6,7-isomer) was dissolved in 3 mL of methanol and 1.00 M sodium hydroxide in methanol (0.80 mL, 0.80 mmol) was added. The solution was stirred under reflux for 3 hr. The solvent was evaporated in vacuo yielding 0.15 g of sodium 6,8-dihydroxyoctanoate as a white powder. Yield was quantitative.

後処理

  1. temperatureunder reflux for 3 hr
  2. customThe solvent was evaporated in vacuo

出典と根拠

ORDレコード
ord-48a55d2b2b2143169c415ce09cccbe75
出典データセット
uspto-grants-2001_12
特許番号
US06331559B1

反応ノート

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