HCID 75480723、化合物 → 5-(Pyrrolidin-1-yl)pyridin-2-amine
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:14][CH2:13][CH2:12][CH2:11]2)=[CH:6][N:5]=1)([O-])=O>[Pd]>[N:10]1([C:7]2[CH:8]=[CH:9][C:4]([NH2:1])=[N:5][CH:6]=2)[CH2:14][CH2:13][CH2:12][CH2:11]1参加物
3
実験手順
410 mg (2.12 mmol) of the product obtained in step 25.1 are hydrogenated in the presence of 10% Pd/C at atmospheric pressure at 35° C. The solution obtained is evaporated under reduced pressure to give 321 mg of 5-pyrrolidin-1-ylpyridin-2-ylamine.
後処理
- customThe solution obtained
- customis evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-8d3f3af05ba7426988771a7bdc2ec61c
- 出典データセット
- uspto-grants-2015_09
- 特許番号
- US09120812B2
反応ノート
読み込み中…