2-Methoxyethylamine → N-(2-Methoxyethyl)-2-nitroaniline
反応式
[CH3:1][O:2][CH2:3][CH2:4][NH2:5].F[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N+:13]([O-:15])=[O:14]>C(O)C>[CH3:1][O:2][CH2:3][CH2:4][NH:5][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N+:13]([O-:15])=[O:14]参加物
4
実験手順
2-methoxyethaneamine (3 mL) is added to a solution of 1-fluoro-2-nitrobenzene (400 mg, 2.84 mmol) in ethanol. The reaction may be stirred at room temperature for an appropriate time period (such as overnight) and concentrated. The residue may be purified by any appropriate method including Biotage column chromatography to give N-(2-methoxyethyl)-2-nitroaniline (477 mg).
後処理
- customThe reaction
- concentrationconcentrated
- customThe residue may be purified by any appropriate method
出典と根拠
- ORDレコード
- ord-ea8506d4311a492ba5cc7a4ca47f8f31
- 出典データセット
- uspto-grants-2015_09
- 特許番号
- US09125901B2
反応ノート
読み込み中…