Sodium Hydroxide → 3-(3-Fluorophenyl)-5-methylisoxazole-4-carboxylic acid
反応式
C[O:2][C:3]([C:5]1[C:6]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([F:17])[CH:12]=2)=[N:7][O:8][C:9]=1[CH3:10])=[O:4].[OH-].[Na+]>CO>[F:17][C:13]1[CH:12]=[C:11]([C:6]2[C:5]([C:3]([OH:4])=[O:2])=[C:9]([CH3:10])[O:8][N:7]=2)[CH:16]=[CH:15][CH:14]=1参加物
4
実験手順
In a similar manner as described in Preparation Example 25, by using methanol (60 mL), methyl-3-(3-fluorophenyl)-5-methylisoxazol-4-carboxylate (6.0 g, 25.51 mmol) and 3% sodium hydroxide aqueous solution (60 mL), a white solid required compound (5.21 g, 23.44 mmol, 92%) was obtained.
後処理
- customIn a similar manner as described in Preparation Example 25
出典と根拠
- ORDレコード
- ord-b566705dec074fdd83da69c12ab9f4ed
- 出典データセット
- uspto-grants-2015_09
- 特許番号
- US09132126B2
反応ノート
読み込み中…