Acetone Cyanohydrin → 1-Benzyl-5-isopropyl-2,2-dimethyl-piperazine

反応式

[CH2:1](N1CC(C)(C)NCC21CCCC2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:20][CH:21]([CH3:26])[CH:22]([NH2:25])[CH2:23][NH2:24].[CH3:27][C:28]([CH3:32])(O)[C:29]#N>>[CH2:1]([N:24]1[CH2:23][CH:22]([CH:21]([CH3:26])[CH3:20])[NH:25][CH2:27][C:28]1([CH3:32])[CH3:29])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

反応物 3

HCID 6406Acetone Cyanohydrin

HCID 30642243-Methylbutane-1,2-diamine

HCID 64842474HCID 64842474、化合物

生成物 1

HCID 648378971-Benzyl-5-isopropyl-2,2-dimethyl-piperazine

実験手順

1-Benzyl-5-isopropyl-2,2-dimethyl-piperazine was synthesized in analogy to 6-benzyl-8,8-dimethyl-6,9-diaza-spiro[4.5]decane starting from 3-methyl-butane-1,2-diamine and acetone cyanohydrin.

出典と根拠

ORDレコード: ord-5452a8144d4e4fb48686f8257e4ea82c
出典データセット: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09133181B2

反応ノート

読み込み中…