Thioacetamide → Pyrimidine-2-carbothioamide

HRID 2279646ノート

反応式

HRID 2279646 の反応式
[C:1]([C:3]1[N:8]=[CH:7][CH:6]=[CH:5][N:4]=1)#[N:2].C(N)(=[S:11])C>Cl>[N:4]1[CH:5]=[CH:6][CH:7]=[N:8][C:3]=1[C:1](=[S:11])[NH2:2]

参加物

4

反応物 2

HCID 2723949ThioacetamideHCID 27579792-Cyanopyrimidine

生成物 1

HCID 23273397Pyrimidine-2-carbothioamide

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

反応条件

温度
90 °C

実験手順

A mixture of 2-cyanopyrimidine (15 g) and thioacetamide (20 g) in 100 mL of 10% concentrated HCl in Miff is heated with stirring at 90° C. for three hours and cooled. The solid is collected by filtration, washed with water and dried to afford the title compound.

後処理

  1. temperatureis heated
  2. temperaturecooled
  3. filtrationThe solid is collected by filtration
  4. washwashed with water
  5. customdried

出典と根拠

ORDレコード
ord-ce581895d9db4aed93601a301b61095a
出典データセット
uspto-grants-2015_09
特許番号
US09133204B2

反応ノート

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