Sodium Bicarbonate → 4-(propylamino)-2-((2-(pyridin-4-yl)ethyl)amino)-N-(3-(2,2,2-trifluoro-N-methylacetamido)phenyl)pyrimidine-5-carboxamide

反応式

[NH2:1][C:2]1[CH:3]=[C:4]([N:8]([CH3:15])[C:9](=[O:14])[C:10]([F:13])([F:12])[F:11])[CH:5]=[CH:6][CH:7]=1.[CH2:16]([NH:19][C:20]1[C:25]([C:26](O)=[O:27])=[CH:24][N:23]=[C:22]([NH:29][CH2:30][CH2:31][C:32]2[CH:37]=[CH:36][N:35]=[CH:34][CH:33]=2)[N:21]=1)[CH2:17][CH3:18].Cl.C(N=C=NCCCN(C)C)C.O.ON1C2C=CC=CC=2N=N1.C(=O)([O-])O.[Na+]>C(OCC)(=O)C.C(N(CC)CC)C.CN(C)C=O>[CH2:16]([NH:19][C:20]1[C:25]([C:26]([NH:1][C:2]2[CH:7]=[CH:6][CH:5]=[C:4]([N:8]([CH3:15])[C:9](=[O:14])[C:10]([F:11])([F:12])[F:13])[CH:3]=2)=[O:27])=[CH:24][N:23]=[C:22]([NH:29][CH2:30][CH2:31][C:32]2[CH:33]=[CH:34][N:35]=[CH:36][CH:37]=2)[N:21]=1)[CH2:17][CH3:18]