Pyridine → p-Propylphenyl acetate

4-n-Propylphenol (1.00 g) was dissolved in dichloromethane (10 ml) to prepare a solution. Pyridine (862 mg) and acetyl chloride (692 mg) were added to the solution, and the mixture was stirred at room temperature overnight. The solvent was removed therefrom by distillation under the reduced pressure. Water was then added to the residue, and the mixture was extracted with chloroform. The chloroform layer was washed with water and was dried over anhydrous magnesium sulfate. The solvent was removed therefrom by distillation under the reduced pressure, and the residue was purified by column chromatography using chloroform to give 4-n-propylphenyl acetate (1.09 g, yield 100%).

1. customto prepare a solution
2. customThe solvent was removed
3. distillationby distillation under the reduced pressure
4. additionWater was then added to the residue
5. extractionthe mixture was extracted with chloroform
6. washThe chloroform layer was washed with water
7. dry with materialwas dried over anhydrous magnesium sulfate
8. customThe solvent was removed
9. distillationby distillation under the reduced pressure
10. customthe residue was purified by column chromatography

ORDレコード

ord-9d31589c576b462585f065103706a5ce

出典データセット

uspto-grants-2009_07

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US07560558B2