HCID 54525609、化合物 → HCID 12874030、化合物

HRID 2287269ノート

反応式

HRID 2287269 の反応式
[CH3:1][C:2]1([CH:7]=[CH:8][O:9][C:10](=[O:12])[CH3:11])[NH:5][C:4](=[O:6])[CH2:3]1.[H][H]>C(OCC)(=O)C.[Pd]>[CH3:1][C:2]1([CH2:7][CH2:8][O:9][C:10](=[O:12])[CH3:11])[NH:5][C:4](=[O:6])[CH2:3]1

参加物

5

反応物 2

HCID 54525609HCID 54525609、化合物HCID 178418361HCID 178418361、化合物

生成物 1

HCID 12874030HCID 12874030、化合物

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

A solution of 4-methyl-4-(2-acetoxyvinyl)-2-azetidinone (10.0 g, 0.065 mole) in 200 ml ethyl acetate containing 100 mg of 10% Pd/C is hydrogenated on a Parr shaker at 25° C. under 40 psi hydrogen for 15 minutes. The mixture is filtered through a bed of Supercel and washed with additional ethyl acetate. The combined filtrate is evaporated in vacuo to give 4-methyl-4-(2-acetoxyethyl)-2-azetidinone.

後処理

  1. filtrationThe mixture is filtered through a bed of Supercel
  2. washwashed with additional ethyl acetate
  3. customThe combined filtrate is evaporated in vacuo

出典と根拠

ORDレコード
ord-f01ce45bc8ba4dbfa19ec563ba98f612
出典データセット
uspto-grants-1981_05
特許番号
US04269873

反応ノート

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