methyl 4-[(Z)-2-(4-pyridyl)vinyl]benzoate → Methyl 4-[2-(4-pyridyl)ethyl]benzoate
反応式
[N:1]1[CH:6]=[CH:5][C:4](/[CH:7]=[CH:8]\[C:9]2[CH:18]=[CH:17][C:12]([C:13]([O:15][CH3:16])=[O:14])=[CH:11][CH:10]=2)=[CH:3][CH:2]=1>CO.[Pd]>[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][CH2:8][C:9]2[CH:18]=[CH:17][C:12]([C:13]([O:15][CH3:16])=[O:14])=[CH:11][CH:10]=2)=[CH:3][CH:2]=1参加物
4
実験手順
To a solution of methyl 4-[(Z)-2-(4-pyridyl)vinyl]-benzoate (570 mg) in methanol (5.7 ml) was added 10% palladium on carbon, and the mixture was stirred for 4 hours at ambient temperature under hydrogen atmosphere. Insoluble material was filtered off, and the filtrate was concentrated in vacuo. The residue was crystallized with n-hexane to give methyl 4-[2-(4-pyridyl)ethyl]benzoate (539 mg).
後処理
- filtrationInsoluble material was filtered off
- concentrationthe filtrate was concentrated in vacuo
- customThe residue was crystallized with n-hexane
出典と根拠
- ORDレコード
- ord-6f903535383b4bdfb8fcc5d136dcc81d
- 出典データセット
- uspto-grants-2000_07
- 特許番号
- US06083961
反応ノート
読み込み中…