反応式
[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([CH3:16])[N:11]=2)[OH:9])[O:5][C:6]=1[CH3:7]>C(Cl)(Cl)Cl.[O-2].[O-2].[Mn+4]>[CH3:1][C:2]1[CH:3]=[C:4]([C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([CH3:16])[N:11]=2)=[O:9])[O:5][C:6]=1[CH3:7]参加物
4
実験手順
(4,5-Dimethylfuran-2-yl)-(6-methyl-pyridin-2-yl)-methanol (1.4 g) was dissolved in chloroform (30 ml) to prepare a solution. Manganese dioxide (5.7 g) was added to the solution, and the mixture was stirred at room temperature overnight. Further, manganese dioxide (1.8 g) was then added thereto, and the mixture was stirred overnight. The reaction solution was filtered through Celite. The solvent was removed from the filtrate by distillation under the reduced pressure to give (4,5-dimethylfuran-2-yl)-(6-methyl-pyridin-2-yl)-methanone (815 mg, yield 58%).
後処理
- customto prepare a solution
- stirringthe mixture was stirred overnight
- filtrationThe reaction solution was filtered through Celite
- customThe solvent was removed from the filtrate by distillation under the reduced pressure
出典と根拠
- ORDレコード
- ord-6ab18d8b261b491b95b95d5380da68f3
- 出典データセット
- uspto-grants-2009_07
- 特許番号
- US07560558B2
関連ノート
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