Iodoethane → HCID 178477485、化合物

HRID 2288921ノート

反応式

HRID 2288921 の反応式
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:15]([NH2:17])=[S:16])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I:18][CH2:19][CH3:20]>CC(C)=O>[IH:18].[CH2:19]([S:16][C:15](=[NH:17])[NH:14][C:11]1[CH:12]=[CH:13][C:8]([O:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:9][CH:10]=1)[CH3:20]

参加物

4

反応物 2

HCID 6340IodoethaneHCID 27603494-Phenoxyphenylthiourea

生成物 1

HCID 178477485HCID 178477485、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

To a stirred solution of 1-(4-phenoxyphenyl)-2-thiourea (2.00 g, 8.19 mmol) in acetone (20 ml) was added iodoethane (7.61 g, 48.7 mmol). The mixture was heated to reflux for three hours, cooled to room temperature and concentrated at reduced pressure. The resulting viscous oil was crystallized from acetone-pentane to afford S-ethyl-N-(4-phenoxyphenyl)isothiourea hydroiodide as a beige solid. Mp=140-143° C.

後処理

  1. temperatureThe mixture was heated
  2. temperatureto reflux for three hours
  3. concentrationconcentrated at reduced pressure
  4. customThe resulting viscous oil was crystallized from acetone-pentane

出典と根拠

ORDレコード
ord-7a6304c653db46079f31e2c05d58d57f
出典データセット
uspto-grants-2000_07
特許番号
US06090846

反応ノート

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