4-Nitro-1,3-dihydroisobenzofuran → 4-Amino-1,3-dihydroisobenzofuran
反応式
[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:5]=1[CH2:6][O:7][CH2:8]2)([O-])=O.[H][H]>[Pd]>[NH2:1][C:4]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:5]=1[CH2:6][O:7][CH2:8]2参加物
4
実験手順
Nitration of the 1,3-dihydro-iso-benzofuran derivatives of Formula 17 provides the 1,3-dihydro-4-nitro-iso-benzofuran compounds of Formula 18. The nitro compounds of Formula 18 are reduced with hydrogen on a suitable catalyst, such as palladium, to give the 1,3-dihydro-4-amino-iso-benzofuran compounds of Formula 19.
出典と根拠
- ORDレコード
- ord-7e05cede79f142458dc3fb56cac26c49
- 出典データセット
- uspto-grants-2000_07
- 特許番号
- US06093838
反応ノート
読み込み中…