1,6-Dibromohexane → 4-(6-Bromohexyloxy)-4'-nitrobiphenyl

HRID 2291258

反応式

HRID 2291258 の反応式
[K].[OH:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.[Br:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]Br.C1OCCOCCOCCOCCOCCOC1>C1(C)C=CC=CC=1>[Br:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][CH:10]=2)=[CH:7][CH:8]=1

参加物

6

反応物 4

HCID 123681,6-DibromohexaneHCID 2855718-Crown-6HCID 1380784-Hydroxy-4'-nitrobiphenylHCID 5462222Potassium

生成物 1

HCID 200312344-(6-Bromohexyloxy)-4'-nitrobiphenyl

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

To 500 ml of toluene in a 100 ml round bottom flask, fitted with a condenser and magnetic stirrer, are added 7.6 g (0.03M) of the potassium salt of 4-hydroxy-4'-nitrobiphenyl, 36.6 g (0.15M) of 1,6-dibromohexane, and 0.5 g of 18-crown-6 ether. The mixture is refluxed for about 20 hours, and then filtered hot. The solvent is evaporated, and the residual crude product is recrystallized from hexane to provide purified product.

後処理

  1. temperatureThe mixture is refluxed for about 20 hours
  2. filtrationfiltered hot
  3. customThe solvent is evaporated
  4. customthe residual crude product is recrystallized from hexane
  5. customto provide
  6. custompurified product

出典と根拠

ORDレコード
ord-f360704a57c143c7a3c6b8dd3e9919a2
出典データセット
uspto-grants-1989_01
特許番号
US04795664

関連ノート

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