Hydrochloric Acid → HCID 20031799、化合物
反応式
C([O:4][C:5]1[CH:24]=[CH:23][C:8]([C:9]([O:11][C:12]2[C:17]([F:18])=[C:16]([F:19])[C:15]([F:20])=[C:14]([F:21])[C:13]=2[F:22])=[O:10])=[CH:7][CH:6]=1)(=O)C.Cl>O1CCCC1>[OH:4][C:5]1[CH:24]=[CH:23][C:8]([C:9]([O:11][C:12]2[C:13]([F:22])=[C:14]([F:21])[C:15]([F:20])=[C:16]([F:19])[C:17]=2[F:18])=[O:10])=[CH:7][CH:6]=1参加物
4
実験手順
Pentafluorophenyl 4-acetoxybenzoate (10 g) in tetrahydrofuran was treated with 50 ml of 5M hydrochloric acid and 150 ml of tetrahydrofuran and stirred at room temperature overnight. The solvents were evaporated in vacuo to give a product which was purified by column chromatography (silica; ethyl acetate/hexane mixtures as eluant) to afford the title compound (8 g).
後処理
- customThe solvents were evaporated in vacuo
- customto give a product which
- customwas purified by column chromatography (silica; ethyl acetate/hexane mixtures as eluant)
出典と根拠
- ORDレコード
- ord-f0eba863e7a149a8a74543afb0be07cc
- 出典データセット
- uspto-grants-1989_01
- 特許番号
- US04795748
反応ノート
読み込み中…