Thionyl Chloride → 2,2,5,5-Tetramethylcyclopentanecarbonyl chloride

HRID 2291407ノート

反応式

HRID 2291407 の反応式
[CH3:1][C:2]1([CH3:12])[CH2:6][CH2:5][C:4]([CH3:8])([CH3:7])[CH:3]1[C:9](O)=[O:10].S(Cl)([Cl:15])=O>C1(C)C=CC=CC=1>[CH3:1][C:2]1([CH3:12])[CH2:6][CH2:5][C:4]([CH3:8])([CH3:7])[CH:3]1[C:9]([Cl:15])=[O:10]

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 10197889Cyclopentanecarboxylic acid, 2,2,5,5-tetramethyl-

生成物 1

HCID 139066402,2,5,5-Tetramethylcyclopentanecarbonyl chloride収率 69%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

反応条件

温度
80 °C

実験手順

2.51 g of 2,2,5,5-tetramethylcyclopentanecarboxylic acid was dissolved in 10 ml of toluene, and 2.5 ml of thionyl chloride was added thereto. The mixture was stirred at 80° C. for 3 hours. The reaction solution was concentrated and then distilled under reduced pressure, whereby 2.0 g of 2,2,5,5-tetramethylcyclopentanecarbonyl chloride was obtained. Yield 69%. (b.p. 110-120° C./60 mmHg)

後処理

  1. concentrationThe reaction solution was concentrated
  2. distillationdistilled under reduced pressure

出典と根拠

ORDレコード
ord-67add0a7abff4e40ac592ac9b50345f2
出典データセット
uspto-grants-1989_01
特許番号
US04795831

反応ノート

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