Thionyl Chloride → 2,3,5-Trichlorophenylacetyl chloride

HRID 2292454ノート

反応式

HRID 2292454 の反応式
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([Cl:9])=[CH:4][C:3]=1[CH2:10][C:11]([OH:13])=O.S(Cl)([Cl:16])=O>C(Cl)(Cl)(Cl)Cl>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([Cl:9])=[CH:4][C:3]=1[CH2:10][C:11]([Cl:16])=[O:13]

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 186876252,3,5-Trichlorophenylacetic acid

生成物 1

HCID 214781102,3,5-Trichlorophenylacetyl chloride

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A suspension of 6.0 grams (0.023 mole) of 2,3,5-trichlorophenylacetic acid in about 125 mL of carbon tetrachloride was stirred, and 5 mL of thionyl chloride was added. The reaction mixture was then warmed to reflux, where it was stirred for about 30 minutes. After this time the reaction mixture was concentrated under reduced pressure, yielding 6.4 grams of 2,3,5-trichlorophenylacetyl chloride.

後処理

  1. temperatureThe reaction mixture was then warmed
  2. temperatureto reflux
  3. stirringwhere it was stirred for about 30 minutes
  4. concentrationAfter this time the reaction mixture was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-6ef1d3bad445435d8ca8b375b0971ffd
出典データセット
uspto-grants-1997_11
特許番号
US05683966

反応ノート

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