Tetrahydrofuran → HCID 21476517、化合物
反応式
[H-].[Al+3].[Li+].[H-].[H-].[H-].O1CCCC1.C([O:14][C:15]([CH2:17][NH:18][CH:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH3:27])[CH3:20])=O)C>O>[OH:14][CH2:15][CH2:17][NH:18][CH:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH3:27])[CH3:20]参加物
5
実験手順
To a mixture of 3.8 g of lithium aluminium hydride (0.1M) and 150 ml of tetrahydrofuran, 23.3 g of the compound (0.105M) prepared in Step 2 above was dropwise added at room temperature and stirred for 30 minutes. The resultant was added with water and solids produced were filtered. The filtrate was dried over anhydrous sodium sulfate and concentrated under a reduced pressure, to give 13.8 g of the title compound.
後処理
- additionabove was dropwise added at room temperature
- customproduced
- filtrationwere filtered
- dry with materialThe filtrate was dried over anhydrous sodium sulfate
- concentrationconcentrated under a reduced pressure
出典と根拠
- ORDレコード
- ord-d27c09a32e4e4329baf030e0a5a47bc3
- 出典データセット
- uspto-grants-1997_11
- 特許番号
- US05686458
反応ノート
読み込み中…