N,N-dimethyl-2-nitrobenzamide → 2-Amino-N,N-dimethylbenzamide
反応式
[CH3:1][N:2]([CH3:14])[C:3](=[O:13])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N+:10]([O-])=O>[Pd].C(O)C>[NH2:10][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[C:3]([N:2]([CH3:14])[CH3:1])=[O:13]参加物
4
実験手順
A mixture of N,N-dimethyl-2-nitrobenzamide (4.76 g, 24.5 mmol) and 10% palladium on carbon (470 mg) in 100 mL of ethanol was stirred under hydrogen at atmospheric pressure for approximately 12 hours. The mixture was filtered and concentrated to dryness to give 2-amino-N,N-dimethylbenzamide (4 g, 24.2 mmol), m.p. 53°-54° C.
後処理
- filtrationThe mixture was filtered
- concentrationconcentrated to dryness
出典と根拠
- ORDレコード
- ord-f6451c774b1749d49a417ccd75964742
- 出典データセット
- uspto-grants-1997_11
- 特許番号
- US05688795
反応ノート
読み込み中…