Ammonia → Aklomide

HRID 2295370

反応式

HRID 2295370 の反応式
[Cl:1][C:2]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].[NH3:14]>>[Cl:1][C:2]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:3]=1[C:4]([NH2:14])=[O:5]

参加物

3

反応物 2

HCID 222AmmoniaHCID 81522Benzoyl chloride, 2-chloro-4-nitro-

生成物 1

HCID 2075Aklomide収率 90%

実験手順

Thereafter, 2-chloro-4-nitrobenzoyl chloride (450 g, 2.1 m) was added dropwise to a stirred 28% ammonia solution (2,000 ml) at below room temperature between 9° and 16° C. The precipitated reaction mixture was washed with water and 30% methanol and then vacuum-dried to yield 2-chloro-4-nitrobenzamide (379 g, 90%, mp 168°-170° C.).

後処理

  1. customThe precipitated reaction mixture
  2. washwas washed with water and 30% methanol
  3. customvacuum-dried

出典と根拠

ORDレコード
ord-9cec857d21fd40069e2cb33d97c7ca65
出典データセット
uspto-grants-1984_01
特許番号
US04424371

関連ノート

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