Sodium Hydroxide → HCID 19848366、化合物
反応式
C[O:2][C:3](=[O:17])[CH2:4][O:5][C:6]1[C:11]([Cl:12])=[CH:10][C:9]([Cl:13])=[C:8]([C:14]#[N:15])[C:7]=1[Cl:16].[OH-:18].[Na+]>O>[C:14]([C:8]1[C:7]([Cl:16])=[C:6]([C:11]([Cl:12])=[CH:10][C:9]=1[Cl:13])[O:5][CH2:4][C:3]([OH:2])=[O:17])(=[O:18])[NH2:15]参加物
4
反応条件
- 温度
- 60 °C
実験手順
29.4 g (0.1 mol) of 3-cyano-2,4,6-trichlorophenoxyacetic acid methyl ester are suspended in 300 ml of water. After addition of 35 ml of concentrated sodium hydroxide, the reaction mixture is heated at 60° C. until a clear solution is obtained. After filtration over active carbon, the solution is cooled and brought to pH 2 by dropwise addition of 50% concentrated hydrochloric acid. The mixture is stirred for 2 hours in an ice bath, after which the resultant precipitate is vacuum-filtered, washed with water and dried at 50° C., thus producing 25.4 g (85% of theory) of 3-carbamoyl-2,4,6-trichlorophenoxyacetic acid as a white powder, mp 261°-262° C.