p-Toluenesulfonic acid → 3,3',6,6'-Tetramethyl-2,2'-biphenol

HRID 2297083ノート

反応式

HRID 2297083 の反応式
C([C:5]1[C:10]([CH3:11])=[C:9]([OH:12])[C:8]([C:13]2[C:14]([OH:25])=[C:15]([CH3:24])[C:16](C(C)(C)C)=[CH:17][C:18]=2[CH3:19])=[C:7]([CH3:26])[CH:6]=1)(C)(C)C.C1(C)C=CC(S(O)(=O)=O)=CC=1>O>[CH3:19][C:18]1[CH:17]=[CH:16][C:15]([CH3:24])=[C:14]([OH:25])[C:13]=1[C:8]1[C:9]([OH:12])=[C:10]([CH3:11])[CH:5]=[CH:6][C:7]=1[CH3:26]

参加物

4

反応物 2

HCID 6101p-Toluenesulfonic acidHCID 185446495,5'-Bis(t-butyl)-3,3',6,6'-tetramethyl-2,2'-biphenol

生成物 1

HCID 113569233,3',6,6'-Tetramethyl-2,2'-biphenol

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To a 50 mL flask were added 0.5 g of 5,5′-Bis(t-butyl)-3,3′,6,6′-tetramethyl-2,2′-biphenol, 5 mL of xylenes and 0.05 g of p-toluenesulfonic acid. The mixture was refluxed for about 2 hours. The mixture was cooled and water added. The mixture was extracted with hexanes; the organic layer was washed with water and dried over MgSO4. After removing the solvent, the residue was recrystallized from petroleum ether.

後処理

  1. temperatureThe mixture was refluxed for about 2 hours
  2. temperatureThe mixture was cooled
  3. extractionThe mixture was extracted with hexanes
  4. washthe organic layer was washed with water
  5. dry with materialdried over MgSO4
  6. customAfter removing the solvent
  7. customthe residue was recrystallized from petroleum ether

出典と根拠

ORDレコード
ord-35a99cd3e2f24e8699bdfde0ecadada8
出典データセット
uspto-grants-2002_12
特許番号
US06489517B1

反応ノート

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