p-Toluenesulfonic acid → Allyl-(1-methyl-pent-4-enylidene)-amine Allyl-(1-methyl-pent-4-enyl)-amine

HRID 229790ノート

反応式

HRID 229790 の反応式
[CH3:1][C:2](=O)[CH2:3][CH2:4][CH:5]=[CH2:6].[CH2:8]([NH2:11])[CH:9]=[CH2:10].[C:12]1(C)[CH:17]=[CH:16][C:15](S(O)(=O)=O)=[CH:14][CH:13]=1>C(Cl)Cl>[CH2:8]([NH:11][CH:2]([CH3:1])[CH2:3][CH2:4][CH:5]=[CH2:6])[CH:9]=[CH2:10].[CH2:8]([N:11]=[C:16]([CH3:15])[CH2:17][CH2:12][CH:13]=[CH2:14])[CH:9]=[CH2:10]

参加物

5

反応物 3

HCID 6101p-Toluenesulfonic acidHCID 7853AllylamineHCID 79895-Hexene-2-one

生成物 1

HCID 22036684Allyl-(1-methyl-pent-4-enylidene)-amine Allyl-(1-methyl-pent-4-enyl)-amine

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Hex-5-en-2-one (9.8 g, 11.6 ml, 100 mmol) was added to a stirred solution of allylamine (8.55 mmol, 11.25 ml, 150 mmol), 4 Angstrom molecular sieves (52 g), and p-toluene sulfonic acid (10 mg) in CH2Cl2 (200 ml) and was stirred overnight. The reaction mixture was concentrated in vacuo by rotary evaporation and was used in the next reaction without further purification (13 g, 95%). Electrospray mass spec: M+H+=137.9

後処理

  1. concentrationThe reaction mixture was concentrated in vacuo by rotary evaporation
  2. customwas used in the next reaction without further purification (13 g, 95%)

出典と根拠

ORDレコード
ord-0849a3b1ed544e909d3f11f35a3bce59
出典データセット
uspto-grants-2009_07
特許番号
US07563784B2

反応ノート

読み込み中…