Ethyl (4-iodophenyl)acetate → Ethyl (3'-hydroxybiphenyl-4-yl)acetate

HRID 2307546

反応式

HRID 2307546 の反応式
COC[O:4][C:5]1[CH:6]=[C:7](B(O)O)[CH:8]=[CH:9][CH:10]=1.I[C:15]1[CH:20]=[CH:19][C:18]([CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])=[CH:17][CH:16]=1>>[OH:4][C:5]1[CH:6]=[C:7]([C:15]2[CH:20]=[CH:19][C:18]([CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])=[CH:17][CH:16]=2)[CH:8]=[CH:9][CH:10]=1

参加物

3

反応物 2

HCID 14974990Ethyl (4-iodophenyl)acetateHCID 22606941(3-(Methoxymethoxy)phenyl)boronic acid

生成物 1

HCID 25139319Ethyl (3'-hydroxybiphenyl-4-yl)acetate

実験手順

In a manner similar to that of Example 1(h), by reaction of 543 mg (3.6 mmol) of 3-methoxymethoxyphenylboronic acid with 700 mg (2.4 mmol) of ethyl 4-iodophenylacetate, 630 mg (68%) of the expected ethyl ester are obtained.

後処理

  1. customare obtained

出典と根拠

ORDレコード
ord-7f158b0390ca489a88f2fcd39fa54b93
出典データセット
uspto-grants-2004_12
特許番号
US06831106B1

関連ノート

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