Water → 1-[2-(Benzyloxy)-6-hydroxyphenyl]ethan-1-one
反応式
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([OH:8])[C:3]=1[C:9](=[O:11])[CH3:10].C(=O)([O-])[O-].[K+].[K+].[CH2:18](Br)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.O>CC(C)=O>[CH2:18]([O:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([OH:8])[C:3]=1[C:9](=[O:11])[CH3:10])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1参加物
6
実験手順
To a mixture of 2′,6′-dihydroxyacetophenone (4 g) and potassium carbonate (3.82 g) in acetone (40 mL) was added benzyl bromide (3.13 mL), and the mixture was stirred at room temperature overnight. The reaction mixture was poured into water, and the precipitated crystals were collected by filtration. The crystals were washed with water and n-hexane, and dried under reduced pressure to give the title compound (3.67 g).
後処理
- filtrationthe precipitated crystals were collected by filtration
- washThe crystals were washed with water and n-hexane
- customdried under reduced pressure
出典と根拠
- ORDレコード
- ord-ad510b46ab0447c5abe0f9bfcbc6058e
- 出典データセット
- uspto-grants-2009_07
- 特許番号
- US07566699B2
反応ノート
読み込み中…