5,8-Quinoxalinediol → 5,8-Quinoxalinedione
反応式
[OH:1][C:2]1[CH:11]=[CH:10][C:9]([OH:12])=[C:8]2[C:3]=1[N:4]=[CH:5][CH:6]=[N:7]2>O1CCOCC1.[Ag]=O>[N:4]1[C:3]2[C:2](=[O:1])[CH:11]=[CH:10][C:9](=[O:12])[C:8]=2[N:7]=[CH:6][CH:5]=1参加物
4
実験手順
A 9.2 g portion of 5,8-dihydroxyquinoxaline in 300 ml of p-dioxane was heated at reflux with 16.2 g of silver oxide for 6 hours. The mixture was cooled, then filtered and the filtrate concentrated in vacuo. The residue was slurried with 75 ml of acetone, cooled and the solid collected, washed with acetone and dried, giving 8.0 g of the desired product, mp 172°-173° C.
後処理
- temperatureThe mixture was cooled
- filtrationfiltered
- concentrationthe filtrate concentrated in vacuo
- temperaturecooled
- customthe solid collected
- washwashed with acetone
- customdried
出典と根拠
- ORDレコード
- ord-4af702b11afe44f886ccb056c9d49e3b
- 出典データセット
- uspto-grants-1987_09
- 特許番号
- US04692449
反応ノート
読み込み中…