Ammonium Hydroxide → Benzenesulfonamide, 2-(4-isoxazolyl)-
反応式
[O:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[S:12](Cl)(=[O:14])=[O:13])[CH:3]=[N:2]1.[OH-].[NH4+:17]>O1CCCC1>[O:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[S:12]([NH2:17])(=[O:14])=[O:13])[CH:3]=[N:2]1参加物
4
実験手順
By the procedure of Example 5, 15 g of 2-(isoxazol-4-yl)benzenesulfonyl chloride prepared in Example 12 was reacted with 30 ml of concentrated ammonium hydroxide in 150 ml of tetrahydrofuran to give, after recrystallization from 2-propanol, 11 g of the title compound; m.p. 165°-167° C.
後処理
- customto give
- customafter recrystallization from 2-propanol, 11 g of the title compound
出典と根拠
- ORDレコード
- ord-2dac79afb3234d2d8926f9800c6186e5
- 出典データセット
- uspto-grants-1987_09
- 特許番号
- US04695311
反応ノート
読み込み中…