Hydrochloric Acid → 3-Methoxy-4-(7H-purin-8-yl)benzamide
反応式
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][C:4]=1[C:11]1[NH:19][C:18]2[C:13](=[N:14][CH:15]=[N:16][CH:17]=2)[N:12]=1.Cl.[OH-:21].[Na+]>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([C:9]([NH2:10])=[O:21])[CH:6]=[CH:5][C:4]=1[C:11]1[NH:19][C:18]2[C:13](=[N:14][CH:15]=[N:16][CH:17]=2)[N:12]=1参加物
4
実験手順
One gram of 8-(2'-methoxy-4'-cyano-phenyl)-purine was dissolved in 75 ml of 2N sodium hydroxide solution and refluxed for 15 minutes. Then, the mixture was acidified with hydrochloric acid, and the mixture precipitated was separated into its components by use of silica gel [eluant:methylene chloride/ethanol (7:3 to 1:1)].
後処理
- temperaturerefluxed for 15 minutes
- customthe mixture precipitated
- customwas separated into its components by use of silica gel [eluant:methylene chloride/ethanol (7:3 to 1:1)]
出典と根拠
- ORDレコード
- ord-46072a7ae601409092a8ae54ad079d8c
- 出典データセット
- uspto-grants-1987_09
- 特許番号
- US04696931
反応ノート
読み込み中…