Butylamine → N-Butyl-3-methoxy-4-(7H-purin-8-yl)benzene-1-sulfonamide

HRID 2309889ノート

反応式

HRID 2309889 の反応式
[CH2:1]([NH2:5])[CH2:2][CH2:3][CH3:4].Cl.[CH3:7][O:8][C:9]1[CH:14]=[C:13]([S:15](Cl)(=[O:17])=[O:16])[CH:12]=[CH:11][C:10]=1[C:19]1[NH:27][C:26]2[C:21](=[N:22][CH:23]=[N:24][CH:25]=2)[N:20]=1>>[CH3:7][O:8][C:9]1[CH:14]=[C:13]([S:15]([NH:5][CH2:1][CH2:2][CH2:3][CH3:4])(=[O:17])=[O:16])[CH:12]=[CH:11][C:10]=1[C:19]1[NH:27][C:26]2[C:21](=[N:22][CH:23]=[N:24][CH:25]=2)[N:20]=1

参加物

3

反応物 2

HCID 8007ButylamineHCID 20184500HCID 20184500、化合物

生成物 1

HCID 13284538N-Butyl-3-methoxy-4-(7H-purin-8-yl)benzene-1-sulfonamide

実験手順

Prepared analogously to Example 51 from n-butylamine and 8-(2'-methoxy-4'-chlorosulfonyl-phenyl)-purine hydrochloride. After the reaction finished, the aqueous phase wsa extracted with ethyl acetate. The residue remaining after the ethyl acetate phases were evaporated was digested with ethanol, subjected to suction filtration, and washed with water.

後処理

  1. extractionthe aqueous phase wsa extracted with ethyl acetate
  2. customwere evaporated
  3. filtrationsubjected to suction filtration
  4. washwashed with water

出典と根拠

ORDレコード
ord-be112d36ebf34269bb4d9373b5ffe902
出典データセット
uspto-grants-1987_09
特許番号
US04696931

反応ノート

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