4,4'-Dihydroxybiphenyl → 4'-(2-Methylbutoxy)(1,1'-biphenyl)-4-ol

HRID 231005

反応式

HRID 231005 の反応式
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[CH3:15][CH:16]([CH2:19][CH3:20])[CH2:17]Br.C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH3:15][CH:16]([CH2:19][CH3:20])[CH2:17][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[CH:6][CH:7]=1

参加物

5

反応物 3

HCID 71124,4'-DihydroxybiphenylHCID 11430Potassium CarbonateHCID 252541-Bromo-2-methylbutane

生成物 1

HCID 140938154'-(2-Methylbutoxy)(1,1'-biphenyl)-4-ol収率 58%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 0.20 mole(37.2 g) of 4,4'-dihydroxybiphenyl, 0.10 mole(15.1 g) of the above 2-methyl-1-bromobutane, and 0.60 mole(33.7 g) of potassium carbonate in 300 ml of ethanol was refluxed for 16 hours. After the reaction, the reaction solution was filtered and concentrated, then purified by column chromatography to obtain 4.9 g of 4'-(2-methylbutoxy)-4-hydroxybiphenyl. (yield: 58%)

後処理

  1. customAfter the reaction
  2. filtrationthe reaction solution was filtered
  3. concentrationconcentrated
  4. custompurified by column chromatography

出典と根拠

ORDレコード
ord-7579d4eec5224c2fa2bdb88004109b17
出典データセット
uspto-grants-1989_07
特許番号
US04844835

関連ノート

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