関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Epichlorohydrin | HCID 7835 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 12-Cyclohexyldodecanol | HCID 14877785 | — |
| 触媒 | Hexadecyltrimethylammonium chloride | HCID 8154 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 1,2-Epoxy-3-(12-cyclohexyldodecyloxy)propane | HCID 14877786 | 71.2% |
反応手順
A mixture containing 26.5 g of 12-cyclohexyldodecanol, 27.4 g of epichlorohydrin, 52.6 g of a 50% aqueous sodium hydroxide solution, 2.0 g of cetyltrimethylammonium chloride and 300 ml of toluene is stirred at 60° C. for 24 hours. The resulting reaction mixture is then washed with water, dried and concentrated to leave a residue which in turn is purified by silica gel chromatography to obtain 22.8 g of the captioned compound as a colorless oily substance.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04845219 |
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| 出典データセット | uspto-grants-1989_07 |
|---|
| ORD ID | ord-8d23ce74afe44c119a199939851f91c9 |
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| 出典メモ | uspto-grants-1989_07 |
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