Ethanolamine → 2-(beta-Hydroxyethyl)amino-6-chloronitrobenzene

HRID 231378

反応式

HRID 231378 の反応式
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[N+:9]([O-:11])=[O:10].[CH2:12]([CH2:14][NH2:15])[OH:13]>>[OH:13][CH2:12][CH2:14][NH:15][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[N+:9]([O-:11])=[O:10]

参加物

3

反応物 2

HCID 700EthanolamineHCID 117591,3-Dichloro-2-nitrobenzene

生成物 1

HCID 146668532-(beta-Hydroxyethyl)amino-6-chloronitrobenzene

実験手順

0.04 mole (7.7 g) of 2,6-dichloronitrobenzene in 30 ml of ethanolamine is heated for 8 hours at 70° C. The reaction mixture is poured onto ice, and then extracted with ethyl acetate. After washing and drying, the ethyl acetate phase is evaporated to dryness under vacuum. The dry extract is recrystallized from ethanol. The product obtained melts at 78° C. (literature value 78.5° C.).

後処理

  1. additionThe reaction mixture is poured onto ice
  2. extractionextracted with ethyl acetate
  3. washAfter washing
  4. customdrying
  5. customthe ethyl acetate phase is evaporated to dryness under vacuum
  6. extractionThe dry extract
  7. customis recrystallized from ethanol
  8. customThe product obtained melts at 78° C. (literature value 78.5° C.)

出典と根拠

ORDレコード
ord-f065eb4a22a94e36aba6941f2c8c3e7c
出典データセット
uspto-grants-1989_07
特許番号
US04845293

関連ノート

読み込み中…