Dimethylformamide → 5-chloro-N-[4-[[2-cyano-4-(3-oxomorpholin-4-yl)phenyl]carbamoyl]-2-hydroxycyclopentyl]thiophene-2-carboxamide
反応式
[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[CH3:42][C:43]#[N:44].[Cl:24][c:25]1[cH:26][cH:27][c:28]([C:30](=[O:31])[NH:32][CH:33]2[CH2:34][CH:35]([C:39](=[O:40])[OH:41])[CH2:36][CH:37]2[OH:38])[s:29]1.[NH2:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([N:10]2[C:11](=[O:16])[CH2:12][O:13][CH2:14][CH2:15]2)[cH:8][cH:9]1.[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[NH:1]([c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([N:10]2[C:11](=[O:16])[CH2:12][O:13][CH2:14][CH2:15]2)[cH:8][cH:9]1)[C:39]([CH:35]1[CH2:34][CH:33]([NH:32][C:30]([c:28]2[cH:27][cH:26][c:25]([Cl:24])[s:29]2)=[O:31])[CH:37]([OH:38])[CH2:36]1)=[O:40]
