Water → 2-Azidomethylanthraquinone

HRID 231912ノート

反応式

HRID 231912 の反応式
Cl[CH2:2][C:3]1[CH:16]=[CH:15][C:14]2[C:13](=[O:17])[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6](=[O:18])[C:5]=2[CH:4]=1.[N-:19]=[N+:20]=[N-:21].[Na+].O>CN(C)C=O>[N:19]([CH2:2][C:3]1[CH:16]=[CH:15][C:14]2[C:13](=[O:17])[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6](=[O:18])[C:5]=2[CH:4]=1)=[N+:20]=[N-:21]

参加物

5

反応物 3

HCID 962WaterHCID 33557Sodium AzideHCID 3443112-(Chloromethyl)anthraquinone

生成物 1

HCID 200322122-Azidomethylanthraquinone収率 92.5%

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

反応条件

温度
50 °C

実験手順

10 g (0.039 mole) of 2-chloromethylanthraquinone [prepared according to G. Izoret, Ann. Chim., 7, 180 (1962)] are dissolved in 50 ml of N,N-dimethylformamide (DMF), and 2.53 g (0.039 mole) of sodium azide are added, with stirring. After 1 hour, the temperature is increased to 50° C. and the mixture is stirred at this temperature for 10 hours. 250 ml of water are added and the precipitate is filtered off. 9.5 g (92.3% of theory) of 2-azidomethyl-anthraquinone are obtained;

後処理

  1. stirringthe mixture is stirred at this temperature for 10 hours
  2. filtrationthe precipitate is filtered off

出典と根拠

ORDレコード
ord-e84a37f73a2744169396aa64935a8c32
出典データセット
uspto-grants-1989_07
特許番号
US04849533

反応ノート

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