Hydrochloric Acid → S-(2,4,5-Trichlorophenyl) 4-(hydroxy)thiobenzoate
反応式
C([O:4][C:5]1[CH:22]=[CH:21][C:8]([C:9]([S:11][C:12]2[CH:17]=[C:16]([Cl:18])[C:15]([Cl:19])=[CH:14][C:13]=2[Cl:20])=[O:10])=[CH:7][CH:6]=1)(=O)C.Cl>O1CCCC1>[OH:4][C:5]1[CH:22]=[CH:21][C:8]([C:9]([S:11][C:12]2[CH:17]=[C:16]([Cl:18])[C:15]([Cl:19])=[CH:14][C:13]=2[Cl:20])=[O:10])=[CH:7][CH:6]=1参加物
4
実験手順
S-(2,4,5-Trichlorophenyl) 4-(acetoxy)thiobenzoate (10 g) in tetrahydrofuran was treated with 25 ml of 5.6M hydrochloric acid and stirred at room temperature overnight. The solvents were evaporated in vacuo to give a product which was purified by column chromatography (silica; ethyl acetate-hexane mixtures as eluant) to afford the title compound (5.4 g).
後処理
- customThe solvents were evaporated in vacuo
- customto give a product which
- customwas purified by column chromatography (silica; ethyl acetate-hexane mixtures as eluant)
出典と根拠
- ORDレコード
- ord-c9e72c98bdc84eb39bae8f59c7a67c7d
- 出典データセット
- uspto-grants-1989_07
- 特許番号
- US04849419
反応ノート
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